GRIN2B anticorps (Tyr1474)

N° du produit ABIN540488

Détail du produit anti-GRIN2B anticorps

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Épitope: Tyr1474

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2B est non-conjugé

Application: Immunofluorescence (IF)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of GRIN2B.

Séquence: HVYEK

Specificité: NMDAR2B (Ab-1472) antibody detects endogenous levels of total NMDAR2B protein.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1474 of human GRIN2B.

Information d'application

Indications d'application: Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-GRIN2B (ABIN540488)

Chazot: "The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies." dans: Current medicinal chemistry, Vol. 11, Issue 3, pp. 389-96, (2004) (PubMed).

Kakegawa, Tsuzuki, Iino, Ozawa: "Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells." dans: The European journal of neuroscience, Vol. 17, Issue 4, pp. 887-91, (2003) (PubMed).

Babb, Ying, Mikuni, Nishiyama, Drazba, Bingaman, Wyllie, Wylie, Yacubova: "Brain plasticity and cellular mechanisms of epileptogenesis in human and experimental cortical dysplasia." dans: Epilepsia, Vol. 41 Suppl 6, pp. S76-81, (2000) (PubMed).

Détails sur GRIN2B

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Autre désignation: NMDAR2B (GRIN2B Produits)

Synonymes: anticorps NMDAR2B, anticorps GluN2B, anticorps MRD6, anticorps NR2B, anticorps hNR3, anticorps nmdar2b, anticorps nr2b, anticorps AW490526, anticorps Nmdar2b, anticorps glutamate ionotropic receptor NMDA type subunit 2B, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog, anticorps glutamate receptor, ionotropic, NMDA2B (epsilon 2), anticorps GRIN2B, anticorps Grin2b, anticorps grin2b.L

ID gène: 2904

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity