FAK anticorps (PTK2 Protein tyrosine Kinase 2)

Details for Product anti-PTK2 Antibody No. ABIN4950985
Antigène
  • FADK
  • FAK
  • FAK1
  • FRNK
  • PPP1R71
  • p125FAK
  • pp125FAK
  • PTK2
  • Fadk
  • mKIAA4203
  • fak
  • fak1a
  • ptk2
  • ptk2a
  • wu:fa18c04
  • zgc:66114
  • CG10023
  • CT28129
  • DFAK
  • DFak
  • DFak56
  • Dfak
  • Dfak56
  • DmFAK
  • Dmel\\CG10023
  • Fak56
  • Fak56D
  • fak56
  • protein tyrosine kinase 2
  • protein tyrosine kinase 2 L homeolog
  • PTK2 protein tyrosine kinase 2
  • protein tyrosine kinase 2ab
  • Focal adhesion kinase
  • PTK2
  • ptk2.L
  • Ptk2
  • ptk2ab
  • Fak
Reactivité
Humain, Souris, Rat (Rattus)
836
580
556
45
29
24
15
10
9
8
8
4
3
3
3
3
3
3
1
1
Hôte
Lapin
780
85
3
2
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp FAK est non-conjugé
30
23
23
23
23
23
22
17
17
11
11
11
11
10
5
2
2
1
1
Application
Western Blotting (WB)
586
273
223
145
143
115
66
36
29
19
9
6
3
3
2
Options
Immunogène Amino acids AHALAVDAKNLLDVIDQARLKMLGQTRPH of human PTK2/FAK were used as the immunogen for the FAK antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others FAK products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation FAK / Focal Adhesion Kinase (PTK2 Antibody Extrait)
Sujet PTK2 protein tyrosine kinase 2 (PTK2), also known as Focal Adhesion Kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
UniProt Q05397
Pathways Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Indications d'application Optimal dilution of the FAK antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the FAK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody (ABIN4950985) Western blot testing of 1) rat lung, 2) mouse lung, 3) rat brain, 4) human U20S, 5) h...
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