FRZB anticorps (Frizzled-Related Protein) (AA 176-325)

Details for Product anti-FRZB Antibody No. ABIN4951095
Antigène
  • Frp
  • Sfrp3
  • frezzled
  • fritz
  • frzb-1
  • FRE
  • FRITZ
  • FRP-3
  • FRZB-1
  • FRZB-PEN
  • FRZB1
  • FZRB
  • OS1
  • SFRP3
  • SRFP3
  • hFIZ
  • Frzb-1
  • frizzled-related protein
  • Frzb
  • FRZB
Épitope
AA 176-325
9
4
2
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain
66
29
18
4
3
3
3
3
2
2
2
1
1
1
Hôte
Lapin
47
14
8
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp FRZB est non-conjugé
6
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
60
32
21
5
4
3
2
2
2
2
2
1
1
1
1
Options
Immunogène Amino acids 176-325 of human FRZB were used as the immunogen for the FRZB antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others FRZB products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation FRZB (FRZB Antibody Extrait)
Sujet FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.
UniProt Q92765
Pathways Signalisation WNT, Positive Regulation of fat Cell Differentiation
Indications d'application Optimal dilution of the FRZB antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,ELISA: 0.1-0.5 μg/mL (human protein tested), request BSA-free format for coating
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the FRZB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Frizzled-Related Protein (FRZB) (AA 176-325) antibody (ABIN4951095) Western blot testing of human 1) PANC and 2) U87 cell lysate with FRZB antibody. Expe...
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