FXYD1 anticorps (AA 21-92)

N° du produit ABIN4951107

Détail du produit anti-FXYD1 anticorps

Antigène: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Épitope: AA 21-92

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXYD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids 21-92 of human FXYD1 were used as the immunogen for the FXYD1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the FXYD1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the FXYD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur FXYD1

Antigène: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Autre désignation: FXYD1 (FXYD1 Produits)

Synonymes: anticorps PLM, anticorps 0610012C17Rik, anticorps 1110006M24Rik, anticorps Plm, anticorps Pml, anticorps FXYD domain containing ion transport regulator 1, anticorps FXYD domain-containing ion transport regulator 1, anticorps FXYD1, anticorps Fxyd1

Sujet: Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.

UniProt: O00168