Histone Deacetylase 11 (HDAC11) anticorps

Détails pour le produit réf. ABIN4951281
Antigène
  • CG31119
  • DHDACX
  • Dmel\\CG31119
  • HDAC11
  • HDACX
  • dHDAC11
  • dmHDA403
  • zgc:91942
  • HD11
  • histone deacetylase 11
  • Histone deacetylase 11
  • hypothetical protein
  • HDAC11
  • hdac11
  • CpipJ_CPIJ001619
  • Bm1_15905
  • LOAG_18214
  • Hdac11
Reactivité
Humain, Souris, Rat (Rattus)
96
59
16
4
4
4
4
4
3
2
2
2
2
1
1
Hôte
Lapin
94
17
Clonalité
Polyclonal
Conjugué
Inconjugué
7
6
6
6
6
6
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
101
53
39
10
4
4
3
1
1
1
1
Options
Immunogène Amino acids NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN of human HDAC11 were used as the immunogen for the HDAC11 antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation HDAC11 (HDAC11 Antibody Extrait)
Sujet Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.
UniProt Q96DB2
Indications d'application Optimal dilution of the HDAC11 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the HDAC11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Histone Deacetylase 11 (HDAC11) antibody (ABIN4951281) Western blot testing of rat 1) skeletal muscle, 2) kidney, 3) heart, 4) NRK, and hum...
Image no. 2 for anti-Histone Deacetylase 11 (HDAC11) antibody (ABIN4951281) IHC testing of FFPE rat brain with HDAC11 antibody. HIER: Boil the paraffin sections ...
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