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HINT1 anticorps

HINT1 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4951300
  • Antigène Voir toutes HINT1 Anticorps
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    Reactivité
    • 47
    • 37
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 4
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HINT1 est non-conjugé
    Application
    • 19
    • 15
    • 14
    • 13
    • 9
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogène
    Amino acids HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK of human HINT1 were used as the immunogen for the HINT1 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product HINT1 Anticorps primaire
  • Indications d'application
    Optimal dilution of the HINT1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the HINT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    Autre désignation
    HINT1 (HINT1 Produits)
    Synonymes
    anticorps hint, anticorps pkci-1, anticorps prkcnh1, anticorps HINT, anticorps NMAN, anticorps PKCI-1, anticorps PRKCNH1, anticorps AA673479, anticorps Hint, anticorps Ipk1, anticorps Pkci, anticorps Prkci, anticorps zgc:103764, anticorps CHPKCI, anticorps HINTZ, anticorps PKCIZ, anticorps histidine triad nucleotide binding protein 1, anticorps histidine triad nucleotide binding protein 1 S homeolog, anticorps histidine triad nucleotide binding protein 1-Z, anticorps Histidine triad nucleotide-binding protein 1, anticorps HINT1, anticorps hint1, anticorps Hint1, anticorps hint1.S, anticorps HINT1Z, anticorps hint-1
    Sujet
    Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/b-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells. The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. Several transcript variants, but only one of them protein-coding, have been found for this gene.
    UniProt
    P49773
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