HINT1 anticorps
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- Antigène Voir toutes HINT1 Anticorps
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HINT1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- Amino acids HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK of human HINT1 were used as the immunogen for the HINT1 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product HINT1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the HINT1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the HINT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Autre désignation
- HINT1 (HINT1 Produits)
- Synonymes
- anticorps hint, anticorps pkci-1, anticorps prkcnh1, anticorps HINT, anticorps NMAN, anticorps PKCI-1, anticorps PRKCNH1, anticorps AA673479, anticorps Hint, anticorps Ipk1, anticorps Pkci, anticorps Prkci, anticorps zgc:103764, anticorps CHPKCI, anticorps HINTZ, anticorps PKCIZ, anticorps histidine triad nucleotide binding protein 1, anticorps histidine triad nucleotide binding protein 1 S homeolog, anticorps histidine triad nucleotide binding protein 1-Z, anticorps Histidine triad nucleotide-binding protein 1, anticorps HINT1, anticorps hint1, anticorps Hint1, anticorps hint1.S, anticorps HINT1Z, anticorps hint-1
- Sujet
- Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/b-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells. The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. Several transcript variants, but only one of them protein-coding, have been found for this gene.
- UniProt
- P49773
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