HLA-A anticorps (Major Histocompatibility Complex, Class I, A)

Details for Product anti-HLA-A Antibody No. ABIN4951306
Antigène
  • HLAA
  • major histocompatibility complex, class I, A
  • HLA-A
Reactivité
Humain, Souris, Rat (Rattus)
155
28
9
7
1
Hôte
Lapin
121
46
6
Clonalité
Polyclonal
Conjugué
Cet anticorp HLA-A est non-conjugé
13
7
5
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
73
68
40
34
28
17
10
6
5
4
3
2
2
Options
Immunogène Amino acids EYWDGETRKVKAHSQTHRVDLGTLR of human HLA-A were used as the immunogen for the HLA-A antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others HLA-A products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation HLA-A (HLA-A Antibody Extrait)
Sujet HLA-A, namely HLA A, is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is simply the major histocompatibility complex (MHC) specific to humans. HLA-A is one of three major types of human MHC class I cell surface receptors. The others are HLA-B and HLA-C. And it is critical to the cytotoxic t-cell controlled immune response to viruses and other intracellular pathogens. Because each HLA-A gene has a high affinity for slightly different peptides, certain HLA-As are associated with increased risk, more rapid progression, and/or increased severity of many diseases. For similar reasons, HLA-A matching is essential to successful tissue transplants.
UniProt P01892
Pathways TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Indications d'application Optimal dilution of the HLA-A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the HLA-A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibody (ABIN4951306) IHC testing of FFPE rat intestine with HLA-A antibody. HIER: Boil the paraffin sectio...
Image no. 2 for anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibody (ABIN4951306) Western blot testing of 1) human U87, 2) human HepG2 and 3) mouse brain lysate with H...
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