HRPT2 anticorps (AA 119-520)

N° du produit ABIN4951356

Détail du produit anti-HRPT2 anticorps

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Épitope: AA 119-520

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRPT2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids 119-520 of human HRPT2 were used as the immunogen for the HRPT2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HRPT2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HRPT2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HRPT2

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Autre désignation: HRPT2 / CDC73 (CDC73 Produits)

Synonymes: anticorps C1orf28, anticorps HPTJT, anticorps HRPT2, anticorps HYX, anticorps 8430414L16Rik, anticorps BC027756, anticorps C130030P16Rik, anticorps C81219, anticorps Hrpt2, anticorps hrpt2, anticorps zgc:63956, anticorps MGC108428, anticorps cdc73, anticorps LOC100222932, anticorps cell division cycle 73, anticorps cell division cycle 73, Paf1/RNA polymerase II complex component, anticorps cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), anticorps parafibromin, anticorps cell division cycle 73 S homeolog, anticorps CDC73, anticorps Cdc73, anticorps cdc73, anticorps Tsp_03925, anticorps Tsp_04052, anticorps Tsp_04125, anticorps cdc73.S

Sujet: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance