Cell Division Cycle 73, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (CDC73) (AA 119-520) anticorps

Détails pour le produit réf. ABIN4951356
Antigène
  • C1orf28
  • HPTJT
  • HRPT2
  • HYX
  • 8430414L16Rik
  • BC027756
  • C130030P16Rik
  • C81219
  • Hrpt2
  • hrpt2
  • zgc:63956
  • MGC108428
  • cdc73
  • LOC100222932
  • cell division cycle 73
  • cell division cycle 73, Paf1/RNA polymerase II complex component
  • cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • parafibromin
  • cell division cycle 73 S homeolog
  • CDC73
  • Cdc73
  • cdc73
  • Tsp_03925
  • Tsp_04052
  • Tsp_04125
  • cdc73.S
Épitope
AA 119-520
9
7
7
7
4
3
1
1
1
1
1
1
1
1
Reactivité
Humain
66
37
33
5
5
5
5
4
2
1
1
1
1
1
Hôte
Lapin
66
1
1
Clonalité
Polyclonal
Conjugué
Inconjugué
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
46
28
26
22
20
13
6
5
3
1
1
Options
Immunogène Amino acids 119-520 of human HRPT2 were used as the immunogen for the HRPT2 antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation HRPT2 / CDC73 (CDC73 Antibody Extrait)
Sujet Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
UniProt Q6P1J9
Pathways Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
Indications d'application Optimal dilution of the HRPT2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the HRPT2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Cell Division Cycle 73, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (CDC73) (AA 119-520) antibody (ABIN4951356) Western blot testing of 1) human placenta, 2) HepG2, 3) 293 and 4) HeLa lysate with H...
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