HSPA8 anticorps (Heat Shock 70kDa Protein 8) (AA 520-614)

Details for Product anti-HSPA8 Antibody No. ABIN4951359
Antigène
  • hsc54
  • hsc70
  • hsc71
  • hsp71
  • hsp73
  • hspa10
  • lap1
  • nip71
  • HSC54
  • HSC70
  • HSC71
  • HSP71
  • HSP73
  • HSPA10
  • LAP1
  • NIP71
  • Hsc70
  • 2410008N15Rik
  • Hsc71
  • Hsc73
  • Hsp73
  • Hspa10
  • wu:fb01g06
  • wu:fi48b06
  • heat shock protein family A (Hsp70) member 8 L homeolog
  • heat shock protein family A (Hsp70) member 8
  • heat shock 70kDa protein 8
  • heat shock protein 8
  • hspa8.L
  • HSPA8
  • Hspa8
  • hspa8
Épitope
AA 520-614
42
31
24
21
11
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
250
193
189
58
35
25
18
18
16
15
14
13
7
5
4
4
4
4
2
2
2
2
2
1
1
1
1
Hôte
Lapin
206
66
12
9
Clonalité
Polyclonal
Conjugué
Cet anticorp HSPA8 est non-conjugé
23
17
7
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
269
164
105
92
77
74
42
37
30
24
24
24
15
5
4
3
3
1
1
Options
Immunogène Amino acids 520-614 of human HSPA8/HSC70 were used as the immunogen for the HSC70 antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others HSPA8 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation HSC70 / HSPA8 (HSPA8 Antibody Extrait)
Sujet HSPA8 (heat shock 70 kDa protein 8) also known as HSC70, HSC71, HSP73, HSPA10, FORMERLY, LAP1 or LPS-ASSOCIATED PROTEIN 1, is a heat shock protein that in humans is encoded by the HSPA8 gene. The HSPA8 gene contains 9 exons and spans 5 kb. The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70,899 Da. And the HSPA8 gene is mapped on 11q24.1. HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding. HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Rapid decay involves AU-rich binding protein AUF1, which complexes with heat-shock proteins HSC70 and HSP70, translation initiation factor EIF4G, and poly (A)-binding protein. In the absence of Il3, Hsc70 formed a complex with Hsp40 and Hip, and this complex, in association with Eif4g and Pabp, formed a high-stability complex with Bim mRNA that protected it from ribonucleases.
UniProt P11142
Indications d'application Optimal dilution of the HSC70 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the HSC70 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 520-614) antibody (ABIN4951359) Western blot testing of 1) rat liver, 2) rat thymus, 3) rat testis, 4) mouse liver, 5...
Image no. 2 for anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 520-614) antibody (ABIN4951359) IHC testing of FFPE rat kidney with HSC70 antibody. HIER: Boil the paraffin sections ...
Image no. 3 for anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 520-614) antibody (ABIN4951359) IHC testing of FFPE mouse kidney with HSC70 antibody. HIER: Boil the paraffin section...
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