IDH2 anticorps (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial)

Details for Product anti-IDH2 Antibody No. ABIN4951404
Antigène
  • F6P23.14
  • F6P23_14
  • IDH-II
  • NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2
  • isocitrate dehydrogenase II
  • isocitrate dehydrogenase subunit 2
  • D2HGA2
  • ICD-M
  • IDH
  • IDHM
  • IDP
  • IDPM
  • mNADP-IDH
  • E430004F23
  • IDPm
  • Idh-2
  • wu:fb33c06
  • wu:fk31e05
  • wu:fq43b01
  • zgc:55485
  • idh2
  • IDH2
  • isocitrate dehydrogenase subunit 2
  • isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog
  • isocitrate dehydrogenase [NADP], mitochondrial
  • IDH2
  • Idh2
  • idh2.S
  • idh2
  • LOC100441867
Reactivité
Humain, Souris, Rat (Rattus)
107
80
67
6
4
2
2
2
2
2
2
1
1
1
1
1
Hôte
Lapin
92
10
7
Clonalité
Polyclonal
Conjugué
Cet anticorp IDH2 est non-conjugé
5
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
79
45
34
16
13
13
8
7
5
2
1
1
1
1
Options
Immunogène Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR of human IDH2 were used as the immunogen for the IDH2 antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation IDH2 (IDH2 Antibody Extrait)
Sujet Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
UniProt P48735
Indications d'application Optimal dilution of the IDH2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the IDH2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) IHC testing of FFPE mouse intestine with IDH2 antibody. HIER: Boil the paraffin secti...
Image no. 2 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) Western blot testing of 1) rat heart, 2) rat liver, 3) mouse NIH3T3, 4) human SW620, ...
Image no. 3 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) IHC testing of frozen human placental tissue with IDH2 antibody.
Image no. 4 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) IHC testing of frozen mouse small intestine tissue with IDH2 antibody.
Image no. 5 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) IHC testing of FFPE rat intestine with IDH2 antibody. HIER: Boil the paraffin section...
Image no. 6 for anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibody (ABIN4951404) IHC testing of frozen rat small intestine tissue with IDH2 antibody.
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