ITCH anticorps (Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse))

Details for Product anti-ITCH Antibody No. ABIN4951494
Antigène
  • AIF4
  • AIP4
  • NAPP1
  • dJ468O1.1
  • 6720481N21Rik
  • 8030492O04Rik
  • A130065M08
  • C230047C07Rik
  • itchy E3 ubiquitin protein ligase
  • itchy, E3 ubiquitin protein ligase
  • ITCH
  • Itch
Reactivité
Humain
70
58
8
3
2
2
1
1
1
1
1
Hôte
Lapin
71
7
6
Clonalité
Polyclonal
Conjugué
Cet anticorp ITCH est non-conjugé
6
5
3
3
3
3
2
2
2
2
2
2
Application
Western Blotting (WB)
55
53
14
6
5
5
3
1
Options
Immunogène Amino acids AMQQFNQRFIYGNQDLFATSQSKEFDPL of human ITCH were used as the immunogen for the ITCH antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others ITCH products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation ITCH / AIF4 (ITCH Antibody Extrait)
Sujet ITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniProt Q96J02
Pathways Activation of Innate immune Response, CXCR4-mediated Signaling Events
Indications d'application Optimal dilution of the ITCH antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the ITCH antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH) antibody (ABIN4951494) Western blot testing of 1) human HeLa, 2) Raji and 3) U937 lysate with ITCH antibody....
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