COPS5 anticorps (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis)) (AA 8-334)

Details for Product anti-COPS5 Antibody No. ABIN4951504
Antigène
  • BcDNA.LD14392
  • BcDNA:LD14392
  • CG14884
  • CH5
  • CSN-5
  • Csn5
  • DCH5
  • Dch5
  • Dmel\\CG14884
  • JAB1
  • JAB1/CSN5
  • Jab1
  • JadBp
  • csn5
  • dch5
  • jab1/csn5
  • l(3)89Cf
  • l(3)L4032
  • l(3)M203
  • quo
  • COPS5
  • MGC76063
  • AI303502
  • CSN5
  • Mov34
  • Sgn5
  • zgc:73130
  • MOV-34
  • SGN5
  • COP9 signalosome subunit 5
  • COP9 signalosome complex subunit 5
  • COP9 signalosome subunit 5 S homeolog
  • CSN5
  • COPS5
  • cops5
  • CpipJ_CPIJ012314
  • Bm1_46585
  • VDBG_06932
  • LOAG_01443
  • csn5
  • Cops5
  • cops5.S
  • csn-5
Épitope
AA 8-334
12
7
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
126
106
63
7
7
6
5
4
4
3
3
3
2
1
1
1
Hôte
Lapin
104
31
2
Clonalité
Polyclonal
Conjugué
Cet anticorp COPS5 est non-conjugé
5
5
5
5
5
5
5
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
46
36
29
24
22
16
4
2
1
1
Options
Immunogène Amino acids 8-334 of human JAB1 were used as the immunogen for the JAB1 antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others COPS5 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation JAB1 (COPS5 Antibody Extrait)
Sujet COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.
UniProt Q92905
Pathways Cycle Cellulaire
Indications d'application Optimal dilution of the JAB1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the JAB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 8-334) antibody (ABIN4951504) Western blot testing of 1) rat testis, 2) mouse testis, 3) human HeLa and 4) 293 lysa...
Image no. 2 for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 8-334) antibody (ABIN4951504) IHC testing of FFPE rat testis with JAB1 antibody. HIER: Boil the paraffin sections i...
Image no. 3 for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 8-334) antibody (ABIN4951504) IHC testing of FFPE mouse testis with JAB1 antibody. HIER: Boil the paraffin sections...
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