KCNA5 anticorps

N° du produit ABIN4951521

Détail du produit anti-KCNA5 anticorps

Antigène: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNA5 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids LEKCNVKAKSNVDLRRSLYALCLDTSRETDL of human KCNA5 were used as the immunogen for the KCNA5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the KCNA5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the KCNA5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KCNA5

Antigène: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Autre désignation: KCNA5 / Kv1.5 (KCNA5 Produits)

Synonymes: anticorps KCNA5, anticorps kcna5, anticorps ATFB7, anticorps HCK1, anticorps HK2, anticorps HPCN1, anticorps KV1.5, anticorps PCN1, anticorps Kv1.5, anticorps Kv1, anticorps potassium voltage-gated channel subfamily A member 5, anticorps potassium channel, voltage gated shaker related subfamily A, member 5, anticorps potassium voltage-gated channel, shaker-related subfamily, member 5, anticorps KCNA5, anticorps kcna5, anticorps Kcna5

Sujet: Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization, thereby contributing to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Mutations in this gene have been related to both atrial fibrillation and sudden cardiac death. KCNA5 are also key players in pulmonary vascular function, where they play a role in setting the resting membrane potential and its involvement during hypoxic pulmonary vasoconstriction.

UniProt: P22460