VEGFR2 anticorps (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase))

Details for Product anti-KDR Antibody No. ABIN4951532
Antigène
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • KDR
  • Kdr
  • LOC100136647
  • kdr
  • kdrl
Reactivité
Humain
625
377
228
28
7
5
5
4
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Hôte
Lapin
586
122
21
2
2
1
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp VEGFR2 est non-conjugé
44
26
25
22
14
12
10
10
10
10
10
10
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Western Blotting (WB)
474
271
268
145
127
104
34
33
27
26
23
19
16
8
8
4
2
1
Options
Immunogène Amino acids LDLPRLSIQKDILTIKANTTLQITCRGQRDLD of human KDR were used as the immunogen for the KDR antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others VEGFR2 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation KDR / Kinase Insert Domain Receptor (KDR Antibody Extrait)
Sujet KDR (Kinase Insert Domain Receptor), also known as FLK1, VEGFR or VEGFR2, is a VEGF receptor. KDR is the human gene encoding it. Sait et al. (1995) likewise corrected the assignment to chromosome 4q11-q12 to the same region occupied also by PDGFRA and KIT, thus indicating the location of a cluster of receptor tyrosine kinase genes. Vascular endothelial growth factor (VEGF) is the only mitogen that specifically acts on endothelial cells. Its expression is upregulated by hypoxia, and its cell-surface receptor, known as fetal liver kinase-1 (Flk1) in mouse, is exclusively expressed in endothelial cells (Plate et al., 1993). Flk1 is the mouse homolog of KDR (Matthews et al., 1991).
UniProt P35968
Pathways Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
Indications d'application Optimal dilution of the KDR antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the KDR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN4951532) Western blot testing of human MCF7 cell lysate with KDR antibody. Expected/observed m...
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