KIF3A anticorps (Kinesin Family Member 3A) (AA 485-699)

Details for Product anti-KIF3A Antibody No. ABIN4951540
Antigène
  • FLA10
  • KLP-20
  • 111-11-71
  • 111-11-86
  • AW124694
  • Kif3
  • Kifl
  • Kns3
  • kinesin family member 3A
  • kinesin family member 3a
  • KIF3A
  • Kif3a
Épitope
AA 485-699
11
9
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
58
33
23
5
3
3
3
3
2
1
1
1
1
1
Hôte
Lapin
57
1
Clonalité
Polyclonal
Conjugué
Cet anticorp KIF3A est non-conjugé
4
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
48
29
18
7
6
2
2
1
Options
Immunogène Amino acids 485-699 of human KIF3A were used as the immunogen for the KIF3A antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others KIF3A products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation KIF3A (KIF3A Antibody Extrait)
Sujet Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. KIF3A is one subunit of the heterotrimeric motor protein, kinesin-2, that was initially isolated from sea urchin egg/embryo cytosol using microtubule affinity purification. This motor consists of two kinesin-related subunits (called KIF3A and KIF3B or 3C in vertebrates) and an associated protein (KAP3), and it transports protein complexes, nucleic acids and organelles towards the plus ends of microtubule tracks within cells. Work done in a broad range of eukaryotic cells has revealed that heterotrimeric kinesin-2 is the primary motor protein driving the intra-flagellar transport of tubulins and other axonemal building blocks from the base of the ciliary/flagellar axoneme to their site of assembly at the distal tips. This process is required for cilium assembly/maintenance and cilium-based signalling which play key roles in various cell and developmental processes. For example, in vertebrate embryos, kinesin-2 function is required for cilia-dependent nodal flow and the development of left-right asymmetry.
UniProt Q9Y496
Pathways Signalisation Hedgehog
Indications d'application Optimal dilution of the KIF3A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the KIF3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Kinesin Family Member 3A (KIF3A) (AA 485-699) antibody (ABIN4951540) Western blot testing of 1) rat brain, 2) rat testis, 3) mouse brain, 4) mouse testis,...
Avez-vous cherché autre chose?