MCM8 anticorps
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- Antigène Voir toutes MCM8 Anticorps
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MCM8 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- Amino acids IQVADFENFIGSLNDQGYLLKKGPKVYQLQTM of human MCM8 were used as the immunogen for the MCM8 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MCM8 Anticorps primaire
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- Indications d'application
- Optimal dilution of the MCM8 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the MCM8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
- Autre désignation
- MCM8 (MCM8 Produits)
- Synonymes
- anticorps C20orf154, anticorps dJ967N21.5, anticorps 5730432L01Rik, anticorps minichromosome maintenance 8 homologous recombination repair factor, anticorps minichromosome maintenance 8 homologous recombination repair factor L homeolog, anticorps MCM8, anticorps Mcm8, anticorps mcm8.L
- Sujet
- DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. And this protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
- UniProt
- Q9UJA3
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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