CCL2 anticorps (AA 24-99)

N° du produit ABIN4951693

Détail du produit anti-CCL2 anticorps

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Épitope: AA 24-99

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity

Immunogène: Amino acids 24-99 of human MCP1 were used as the immunogen for the MCP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MCP1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,ELISA : 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MCP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CCL2

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: CCL2 / MCP1 (CCL2 Produits)

Synonymes: anticorps GDCF-2, anticorps HC11, anticorps HSMCR30, anticorps MCAF, anticorps MCP-1, anticorps MCP1, anticorps SCYA2, anticorps SMC-CF, anticorps AI323594, anticorps JE, anticorps Scya2, anticorps Sigje, anticorps MCP-1A, anticorps MCP1A, anticorps C-C motif chemokine ligand 2, anticorps chemokine (C-C motif) ligand 2, anticorps C-C motif chemokine 2, anticorps CCL2, anticorps Ccl2, anticorps LOC101120093

Sujet: Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, and MCAF. It is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2