Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) anticorps

Détails pour le produit réf. ABIN4951693
Antigène
Épitope
AA 24-99
37
18
15
10
9
7
6
5
4
3
3
3
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain
312
100
65
20
12
11
7
5
3
3
3
2
1
1
1
Hôte
Lapin
282
150
11
10
8
4
3
Clonalité
Polyclonal
Conjugué
Inconjugué
68
33
20
5
5
5
5
5
5
5
5
4
2
2
Application
ELISA, Western Blotting (WB)
355
261
139
53
48
31
30
29
29
25
23
22
22
8
3
3
2
2
1
1
1
Options
Immunogène Amino acids 24-99 of human MCP1 were used as the immunogen for the MCP1 antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation CCL2 / MCP1 (CCL2 Antibody Extrait)
Sujet Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, and MCAF. It is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.
UniProt P13500
Pathways Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded protein response
Indications d'application Optimal dilution of the MCP1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,ELISA : 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the MCP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibody (ABIN4951693) Western blot testing of human SW620 cell lysate with MCP1 antibody. Expected/observed...