Myocyte Enhancer Factor 2A (MEF2A) anticorps

Détails pour le produit réf. ABIN4951701
Antigène
  • ADCAD1
  • RSRFC4
  • RSRFC9
  • mef2
  • A430079H05Rik
  • mef2a
  • wu:fd19d02
  • adcad1
  • rsrfc4
  • rsrfc9
  • sl2
  • MEF2A
  • xmef2a
  • myocyte enhancer factor 2A
  • myocyte enhancer factor 2aa
  • myocyte enhancer factor 2a
  • myocyte-specific enhancer factor 2A
  • myocyte-specific enhancer factor 2a, putative
  • myocyte enhancer factor 2A L homeolog
  • MEF2A
  • Mef2a
  • mef2aa
  • EDI_092490
  • EDI_038250
  • Smp_161530
  • mef2a.L
  • mef2a
  • LOC539054
Reactivité
Humain, Souris, Rat (Rattus)
297
209
177
17
13
12
12
11
11
8
8
6
5
3
3
2
2
Hôte
Lapin
265
35
Clonalité
Polyclonal
Conjugué
Inconjugué
10
8
8
8
8
8
8
4
4
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
183
137
97
74
57
26
14
12
11
7
7
2
Options
Immunogène Amino acids DGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT from the human protein were used as the immunogen for the MEF2A antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation MEF2A / Myocyte-specific enhancer factor 2A (MEF2A Antibody Extrait)
Sujet Myocyte-specific enhancer factor 2A is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter. [UniProt]
UniProt Q02078
Pathways Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Indications d'application Optimal dilution of the MEF2A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the MEF2A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Myocyte Enhancer Factor 2A (MEF2A) antibody (ABIN4951701) IHC testing of FFPE human glioma tissue with MEF2A antibody. HIER: Boil the paraffin ...
Image no. 2 for anti-Myocyte Enhancer Factor 2A (MEF2A) antibody (ABIN4951701) IHC testing of FFPE mouse brain with MEF2A antibody. HIER: Boil the paraffin sections...
Image no. 3 for anti-Myocyte Enhancer Factor 2A (MEF2A) antibody (ABIN4951701) Western blot testing of 1) rat thymus and 2) human HeLa lysate with MEF2A antibody. E...
Image no. 4 for anti-Myocyte Enhancer Factor 2A (MEF2A) antibody (ABIN4951701) IHC testing of FFPE rat brain with MEF2A antibody. HIER: Boil the paraffin sections i...
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