GLUT1 anticorps (AA 92-492)

N° du produit ABIN4952587

Détail du produit anti-GLUT1 anticorps

Antigène: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Épitope: AA 92-492

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUT1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogène: Amino acids 92-492 of human SLC2A1 were used as the immunogen for the SLC2A1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SLC2A1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SLC2A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GLUT1

Antigène: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Autre désignation: GLUT1 / SLC2A1 (SLC2A1 Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps Glut-1, anticorps Glut1, anticorps GLUTB, anticorps GTG1, anticorps Gtg3, anticorps RATGTG1, anticorps SLC2A1, anticorps GLT1, anticorps GLUCOSE TRANSPORTER 1, anticorps T21H19.70, anticorps T21H19_70, anticorps plastidic GLC translocator, anticorps glut1, anticorps ped, anticorps slc2a1, anticorps slc2a14, anticorps solute carrier family 2 member 1, anticorps solute carrier family 2 (facilitated glucose transporter), member 1, anticorps plastidic GLC translocator, anticorps solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog, anticorps SLC2A1, anticorps Slc2a1, anticorps PGLCT, anticorps slc2a1.L

Sujet: GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.

UniProt: P11166

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, L'effet Warburg