ABCB4 anticorps (AA 624-654)

N° du produit ABIN3030051

Détail du produit anti-ABCB4 anticorps

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Épitope: AA 624-654

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Purified

Immunogène: A portion of amino acids 624-654 from the human protein was used as the immunogen for this ABCB4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ABCB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ABCB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ABCB4

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Autre désignation: ABCB4 (ABCB4 Produits)

Synonymes: anticorps ABC21, anticorps GBD1, anticorps ICP3, anticorps MDR2, anticorps MDR2/3, anticorps MDR3, anticorps PFIC-3, anticorps PGY3, anticorps zgc:172149, anticorps Mdr2, anticorps Pgy-2, anticorps Pgy2, anticorps mdr-2, anticorps Pgy3, anticorps ABCB4a, anticorps DEFB1, anticorps PGP2, anticorps PGY2, anticorps PGP3, anticorps ABCB4, anticorps RUNDC3B, anticorps ATP binding cassette subfamily B member 4, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 4, anticorps beta-defensin 1-like, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps RUN domain-containing protein 3B, anticorps ABCB4, anticorps abcb4, anticorps Abcb4, anticorps LOC100861170, anticorps Abcb1b, anticorps LOC101122517

Sujet: The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha