ABCB7
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
HRP
Indications d'application
Titration of the ABCB7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the ABCB7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
ABCB7
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))
anticorps CG7955, anticorps Dmel\\CG7955, anticorps dABCB7, anticorps GB11034, anticorps ABCB7, anticorps fc20c02, anticorps wu:fc20c02, anticorps ABC7, anticorps ASAT, anticorps Atm1p, anticorps EST140535, anticorps AA517758, anticorps AU019072, anticorps Abc7, anticorps ATP binding cassette subfamily B member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial-like, anticorps ABCB7, anticorps LOC412749, anticorps abcb7, anticorps LOC100367778, anticorps LOC100467128, anticorps Abcb7
Sujet
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.