Titration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the ALK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
anticorps ACVRL1, anticorps vgb, anticorps alk1, anticorps zehn1109, anticorps hm:zehn1109, anticorps ACVRLK1, anticorps ALK-1, anticorps ALK1, anticorps HHT, anticorps HHT2, anticorps ORW2, anticorps SKR3, anticorps TSR-I, anticorps R-3, anticorps R3, anticorps SETHKIR, anticorps AI115505, anticorps AI427544, anticorps Acvrlk1, anticorps Alk1, anticorps activin A receptor like type 1, anticorps activin A receptor type II-like 1, anticorps activin A receptor, type II-like 1, anticorps ACVRL1, anticorps acvrl1, anticorps Acvrl1
Sujet
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.