PRKAA1 anticorps (AA 479-510)

N° du produit ABIN3032383

Détail du produit anti-PRKAA1 anticorps

Antigène: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Épitope: AA 479-510

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogène: A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the AMPK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PRKAA1

Antigène: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Autre désignation: AMPK (PRKAA1) (PRKAA1 Produits)

Synonymes: anticorps AMPK, anticorps AMPKa1, anticorps cb116, anticorps im:7154392, anticorps sb:cb130, anticorps wu:fa94c10, anticorps AMPK1, anticorps AMPKalpha1, anticorps AI194361, anticorps AI450832, anticorps AL024255, anticorps C130083N04Rik, anticorps ampk, anticorps ampka1, anticorps PRKAA1, anticorps protein kinase AMP-activated catalytic subunit alpha 1, anticorps protein kinase, AMP-activated, alpha 1 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog, anticorps PRKAA1, anticorps prkaa1, anticorps Prkaa1, anticorps prkaa1.L

Sujet: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.

UniProt: Q13131

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg