CYP1A1 anticorps (AA 252-280)

N° du produit ABIN3030671

Détail du produit anti-CYP1A1 anticorps

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Épitope: AA 252-280

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Purified

Immunogène: A portion of amino acids 252-280 from the human protein was used as the immunogen for this CYP1A1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CYP1A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CYP1A1

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Autre désignation: CYP1A1 (CYP1A1 Produits)

Synonymes: anticorps AHH, anticorps AHRR, anticorps CP11, anticorps CYP1, anticorps P1-450, anticorps P450-C, anticorps P450DX, anticorps Cyp1a2, anticorps P450-1, anticorps cyp1a1, anticorps CYP1A1, anticorps CYPIA1, anticorps Cyp45c, anticorps Cypc45c, anticorps P-450MC, anticorps wu:fb63b04, anticorps zfCYP1A, anticorps zgc:109747, anticorps ahh, anticorps ahrr, anticorps cp11, anticorps cyp1, anticorps cyp1a, anticorps p1-450, anticorps p450-c, anticorps p450dx, anticorps cytochrome P450 family 1 subfamily A member 1, anticorps cytochrome P450 1A1, anticorps cytochrome P450, family 1, subfamily a, polypeptide 1, anticorps cytochrome P450, family 1, subfamily A, polypeptide 1, anticorps cytochrome P450 family 1 subfamily D polypeptide 1, anticorps cytochrome P4501A1, anticorps polycyclic hydrocarbon-inducible cytochrome P450c, anticorps cytochrome P450, family 1, subfamily A, anticorps cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1, anticorps cytochrome P450 family 1 subfamily A member 1 L homeolog, anticorps CYP1A1, anticorps CpipJ_CPIJ010542, anticorps Cyp1a1, anticorps cyp1d1, anticorps LOC100328613, anticorps cyp1a, anticorps LOC102129994, anticorps cyp1a1.L

Sujet: CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.

UniProt: P04798

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha