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PTPN1 anticorps

PTPN1 Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032393
  • Antigène Voir toutes PTPN1 Anticorps
    PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
    Reactivité
    • 103
    • 67
    • 50
    • 16
    • 12
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 99
    • 8
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 95
    • 17
    Polyclonal
    Conjugué
    • 60
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTPN1 est non-conjugé
    Application
    • 80
    • 35
    • 25
    • 24
    • 15
    • 14
    • 13
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Purified
    Immunogène
    This PTP1B antibody was produced from rabbits immunized with a recombinant protein encoding aa 1~321 of human PTP1B.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PTPN1 Anticorps primaire
  • Indications d'application
    Titration of the PTP1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the PTP1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
    Autre désignation
    PTP1B (PTPN1 Produits)
    Synonymes
    anticorps PTPN1, anticorps PTP1B, anticorps PTP-1B, anticorps PTP-HA2, anticorps Ptp, anticorps ptp1b, anticorps wu:fk54h03, anticorps CPTP1, anticorps protein tyrosine phosphatase, non-receptor type 1, anticorps protein tyrosine phosphatase, non-receptor type 1 L homeolog, anticorps PTPN1, anticorps Ptpn1, anticorps ptpn1, anticorps ptpn1.L
    Sujet
    PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
    UniProt
    P18031
    Pathways
    Signalisation TLR, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling
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