IGFBP7 anticorps (Internal Region)

N° du produit ABIN498022

Détail du produit anti-IGFBP7 anticorps

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Épitope: AA 145-159, Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: EKAITQVSKG TCEQG

Specificité: Recognizes IGFBP7 (145-159).

Réactivité croisée (Details): Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_006423.1. Genename: IGFBP7

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 1-3 μg/mL. Approx 30 kDa band observed in Mouse Kidney lysates (calculatedMW of 29.0 kDa according to Human NP_001544.1 and to Mouse NP_032074.3).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGFBP7

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Autre désignation: IGFBP7 (IGFBP7 Produits)

Synonymes: anticorps zgc:85888, anticorps AGM, anticorps FSTL2, anticorps IBP-7, anticorps IGFBP-7, anticorps IGFBP-7v, anticorps IGFBPRP1, anticorps MAC25, anticorps PSF, anticorps RAMSVPS, anticorps TAF, anticorps Fstl2, anticorps Mac25, anticorps insulin like growth factor binding protein 7, anticorps insulin-like growth factor binding protein 7, anticorps IGFBP7, anticorps igfbp7, anticorps Igfbp7

Sujet: IGF-BPs form high affinity complexes with both IGF-I and IGF-II and act to control of the distribution, function and activity of IGFs in various cell tissues and body fluids. There are seven named IGF-BPs. IGFBP7 plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. IGFBP7 is expressed in a wide range of normal human tissues and it usually shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin.Synonyms: IBP-7, IBP7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, Insulin-like growth factor-binding protein 7, MAC25, PGI2-stimulating factor, PSF, Prostacyclin-stimulating factor, TAF, Tumor-derived adhesion factor

ID gène: 3490

NCBI Accession: NP_001544

UniProt: Q16270

Pathways: Growth Factor Binding