GTF2H1 anticorps
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- Antigène Voir toutes GTF2H1 Anticorps
- GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GTF2H1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of TFIIH p62 protein. (region surrounding Ala32)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product GTF2H1 Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
- Autre désignation
- GTF2H1 / BTF2 (GTF2H1 Produits)
- Synonymes
- anticorps 62kDa, anticorps AW743425, anticorps AW822074, anticorps BTF2 p62, anticorps C77871, anticorps p62, anticorps GTF2H1, anticorps BTF2, anticorps P62, anticorps TFB1, anticorps TFIIH, anticorps gtf2h1, anticorps MGC53309, anticorps btf2, anticorps tfiih, anticorps CG8151, anticorps Dmel\\CG8151, anticorps Dmp62, anticorps TfBl, anticorps l(2)06949, anticorps l(2)06950, anticorps zgc:92126, anticorps general transcription factor IIH subunit 1, anticorps general transcription factor II H, polypeptide 1, anticorps general transcription factor IIH subunit 1 L homeolog, anticorps Transcription factor B1, anticorps general transcription factor IIH, polypeptide 1, anticorps GTF2H1, anticorps Gtf2h1, anticorps gtf2h1.L, anticorps gtf2h1, anticorps Tfb1
- Sujet
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription actors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.Synonyms: BTF2-p62, Basic transcription factor 2 62 kDa subunit, General transcription factor IIH polypeptide 1, General transcription factor IIH subunit 1, TFIIH, TFIIH basal transcription factor complex p62 subunit
- Poids moléculaire
- approx. 57 kDa
- ID gène
- 2965
- NCBI Accession
- NP_001135779
- UniProt
- P32780
- Pathways
- Réparation de l'ADN
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