FOXL1 anticorps

N° du produit ABIN498334

Détail du produit anti-FOXL1 anticorps

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of FoxL1 protein. (region surrounding Gly150)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur FOXL1

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Autre désignation: FOXL1 / FKHL11 (FOXL1 Produits)

Synonymes: anticorps zgc:63595, anticorps FOXL1, anticorps fkh6, anticorps fkhl11, anticorps freac7, anticorps CG1132, anticorps Dmel\\CG1132, anticorps Dmfd2, anticorps FD2, anticorps FoxL1, anticorps fd2, anticorps Foxl1, anticorps FKH6, anticorps FKHL11, anticorps FREAC7, anticorps Fkh6, anticorps fkh-6, anticorps forkhead box L1, anticorps forkhead domain 64A, anticorps forkhead transcription factor L1, anticorps forkhead box L1 transcription factor, anticorps foxl1, anticorps FOXL1, anticorps fd64A, anticorps LOC579718, anticorps Foxl1

Sujet: FOXL1 is a 337 amino acid protein encoded by the mouse gene Foxl1. FOXL1 belongs to the fork head family and contains one fork head DNA-binding domain. The HNF3/fork head family includes a large number of transcription factors that share a structurally related DNA binding domain. Fork head factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1- deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the adenomatous polyposis coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.Synonyms: FREAC7, Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7

Poids moléculaire: approx. 36 kDa

ID gène: 2300

NCBI Accession: NP_005241

UniProt: Q12952