PRKG2 anticorps

N° du produit ABIN498430

Détail du produit anti-PRKG2 anticorps

Antigène: PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKG2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of cGKii protein. (region surrounding Asp412)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PRKG2

Antigène: PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))

Autre désignation: CGK2 (PRKG2 Produits)

Synonymes: anticorps MGC82580, anticorps PRKG2, anticorps si:dkey-18e17.2, anticorps PRKGR2, anticorps cGKII, anticorps GDPKII, anticorps AW212535, anticorps CGKII, anticorps Prkgr2, anticorps cGK-II, anticorps protein kinase, cGMP-dependent, type II, anticorps protein kinase, cGMP-dependent, type II L homeolog, anticorps cGMP-dependent protein kinase 2, anticorps PRKG2, anticorps prkg2.L, anticorps prkg2, anticorps LOC100541294, anticorps Prkg2

Sujet: CGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP, and mediates a plethora of physiological responses. cGKII has a predicted molecular weight of 86 kD,a and contains a conserved leucine zipper motif at the amino terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport.Synonyms: PRKG2, PRKGR2, Type II cGMP-dependent protein kinase, cGKII, cGMP-dependent protein kinase 2

Poids moléculaire: approx. 90 kDa

ID gène: 5593

NCBI Accession: NP_006250

UniProt: Q13237