ZNF148 anticorps

N° du produit ABIN498436

Détail du produit anti-ZNF148 anticorps

Antigène: ZNF148 (Zinc Finger Protein 148 (ZNF148))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF148 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of ZBP-89 protein. (region surrounding Glu84)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ZNF148

Antigène: ZNF148 (Zinc Finger Protein 148 (ZNF148))

Autre désignation: ZNF148 (ZNF148 Produits)

Synonymes: anticorps BERF-1, anticorps BFCOL1, anticorps HT-BETA, anticorps ZBP-89, anticorps ZFP148, anticorps pHZ-52, anticorps 2210405J08Rik, anticorps AI480666, anticorps AW045217, anticorps Znf148, anticorps Zbp-89, anticorps fb06h05, anticorps wu:fb06h05, anticorps zfp149, anticorps zgc:165342, anticorps SLC12A8, anticorps zinc finger protein 148, anticorps ZNF148, anticorps Zfp148, anticorps znf148

Sujet: ZBP-89, also known as BFCOL1, BERF1 and ZNF 148, is a zinc finger transcription factor that is universally expressed. ZBP-89, a Kruppel-like repressor protein, is the silencer element binding factor for Vimentin. ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1). ZBP-89 expression is induced by trans-retinoic acid or butyrate, which also induces terminal differentiation of colon cancer cells. ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53. ZBP-89 also regulates cell proliferation, in part, through its ability to directly bind the p53 protein and retard its nuclear export. Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells.Synonyms: Transcription factor ZBP-89, ZBP89, Zinc finger DNA-binding protein 89, Zinc finger protein 148

Poids moléculaire: approx. 89 kDa

ID gène: 7707

NCBI Accession: NP_068799

UniProt: Q9UQR1