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ACVR2A anticorps

ACVR2A Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN498661
  • Antigène Voir toutes ACVR2A Anticorps
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    Reactivité
    • 44
    • 40
    • 12
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 58
    • 10
    • 2
    Lapin
    Clonalité
    • 62
    • 8
    Polyclonal
    Conjugué
    • 43
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACVR2A est non-conjugé
    Application
    • 61
    • 27
    • 24
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody detects endogenous levels of ACTRIIA protein. (region surrounding His59)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Pureté
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product ACVR2A Anticorps primaire
  • Indications d'application
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Reichel, Farmer, Gmeiner, Walpurgis, Thevis: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." dans: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).

  • Antigène
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    Autre désignation
    Activin Receptor Type 2A (ACVR2A) (ACVR2A Produits)
    Synonymes
    anticorps ACVR2, anticorps ACVR2A, anticorps XSTK9, anticorps actrii, anticorps acvr2, anticorps ACTRII, anticorps Acvr2, anticorps rActR-II, anticorps actr2a, anticorps acvr2a, anticorps wu:fa02e10, anticorps ActrIIa, anticorps TactrII, anticorps activin A receptor type 2A, anticorps activin A receptor type 2A L homeolog, anticorps activin A receptor type 2Aa, anticorps activin receptor IIA, anticorps ACVR2A, anticorps acvr2a, anticorps Acvr2a, anticorps acvr2a.L, anticorps acvr2aa
    Sujet
    Members of the transforming growth factor beta superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTRIIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.Synonyms: ACTR-IIA, ACTRIIA, Activin A receptor type IIA
    Poids moléculaire
    approx. 48 kDa
    ID gène
    92
    NCBI Accession
    NP_001607
    UniProt
    P27037
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