DHPS anticorps

N° du produit ABIN499058

Détail du produit anti-DHPS anticorps

Antigène: DHPS (Deoxyhypusine Synthase (DHPS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHPS est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of DHS protein. (region surrounding Leu87)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DHPS

Antigène: DHPS (Deoxyhypusine Synthase (DHPS))

Abstract: DHPS Produits

Synonymes: anticorps MGC76269, anticorps zgc:56018, anticorps zgc:77325, anticorps wu:fb52g04, anticorps wu:fj48f12, anticorps zgc:111900, anticorps MGC82178, anticorps DDBDRAFT_0186679, anticorps DDBDRAFT_0266388, anticorps DDB_0186679, anticorps DDB_0266388, anticorps DHS, anticorps DS, anticorps MIG13, anticorps Dhs, anticorps DYS, anticorps EDA22, anticorps K18J17.7, anticorps K18J17_7, anticorps deoxyhypusine synthase, anticorps embryo sac development arrest 22, anticorps deoxyhypusine synthase, anticorps deoxyhypusine synthase S homeolog, anticorps Deoxyhypusine synthase, anticorps DHPS, anticorps dhps, anticorps dhps.S, anticorps SHELL_RS05250, anticorps PF14_0125, anticorps CNJ02480, anticorps Tb10.70.4900, anticorps Tb927.1.870, anticorps MMAH_RS09430, anticorps TAGG_RS03310, anticorps TAGG_RS05175, anticorps Mesil_2448, anticorps Trad_0088, anticorps Igag_1842, anticorps Desac_0724, anticorps MZHIL_RS05480, anticorps MZHIL_RS05835, anticorps MZHIL_RS06250, anticorps Dhps, anticorps DHS

Sujet: Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.

Poids moléculaire: approx. 45 kDa

ID gène: 1725

NCBI Accession: NP_001921

UniProt: P49366