FOLR1 anticorps
-
- Antigène Voir toutes FOLR1 Anticorps
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
-
Reactivité
- Humain, Rat, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FOLR1 est non-conjugé
-
Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous levels of FR-α (Y80) protein. (region surrounding Tyr80)
- Réactivité croisée (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product FOLR1 Anticorps primaire
-
-
- Indications d'application
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- Autre désignation
- Folate Receptor alpha (FOLR1 Produits)
- Synonymes
- anticorps FBP, anticorps FOLR, anticorps fbp, anticorps folr, anticorps folr1, anticorps FBP1, anticorps Folbp-1, anticorps Folbp1, anticorps Fbp1, anticorps FOLR1, anticorps Folr1, anticorps folate receptor 1, anticorps folate receptor 1 (adult), anticorps folate receptor 1 (adult) L homeolog, anticorps zgc:165502, anticorps Folate receptor alpha, anticorps folate receptor alpha, anticorps FOLR1, anticorps folr1, anticorps folr1.L, anticorps zgc:165502, anticorps Folr1, anticorps LOC100066084, anticorps LOC100725439
- Sujet
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
- Poids moléculaire
- approx. 34 kDa
- ID gène
- 2348
- NCBI Accession
- NP_000793
- UniProt
- P15328
- Pathways
- Dicarboxylic Acid Transport
-