Angiotensin II Type 2 Receptor anticorps (Center)

N° du produit ABIN499231

Détail du produit anti-Angiotensin II Type 2 Receptor anticorps

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type 2 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to AGTR2.

Purification: Affinity chromatography purified via peptide column

Immunogène: AGTR2 antibody was raised against a 16 amino acid peptide from near the center of human AGTR2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: AGTR2 antibody can be used for detection of AGTR2 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Angiotensin II Type 2 Receptor

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Autre désignation: Type-2 Angiotensin II Receptor (AT2) (AGTR2 Produits)

Synonymes: anticorps AT2, anticorps ATGR2, anticorps MRX88, anticorps AI316812, anticorps AW107640, anticorps AT2-R, anticorps AT2R, anticorps AT₂R, anticorps at2, anticorps zgc:113016, anticorps AGTR2, anticorps angiotensin II receptor type 2, anticorps angiotensin II receptor, type 2, anticorps AGTR2, anticorps Agtr2, anticorps agtr2

Sujet: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.Synonyms: AGTR2

ID gène: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones