BCMA anticorps

N° du produit ABIN499437

Détail du produit anti-BCMA anticorps

Antigène: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCMA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: BCMA antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human BCMA Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: BCMA antibody can be used for detection of BCMA at 2 to 5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BCMA

Antigène: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Autre désignation: CD269 / BCMA (TNFRSF17 Produits)

Synonymes: anticorps TNFRSF17, anticorps BCM, anticorps BCMA, anticorps CD269, anticorps TNFRSF13A, anticorps Tnfrsf13, anticorps Tnfrsf13a, anticorps TNF receptor superfamily member 17, anticorps tumor necrosis factor receptor superfamily, member 17, anticorps Tnfrsf17, anticorps TNFRSF17

Sujet: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.Synonyms: B-cell maturation protein, BCM, TNFRSF17, Tumor necrosis factor receptor superfamily member 17

ID gène: 608

NCBI Accession: NP_001183

UniProt: Q02223