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AP2A2 anticorps (AA 21-150) (Alexa Fluor 680)

AP2A2 Reactivité: Humain, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 680
N° du produit ABIN4996394
  • Antigène Voir toutes AP2A2 Anticorps
    AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
    Épitope
    • 14
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-150
    Reactivité
    • 41
    • 28
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 40
    • 1
    Lapin
    Clonalité
    • 41
    Polyclonal
    Conjugué
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AP2A2 est conjugé à/à la Alexa Fluor 680
    Application
    • 33
    • 13
    • 12
    • 12
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificité
    Based on the similarity among the Alpha2-Adaptin proteins, this antibody will bind both AP2A1 and AP2A2.
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AP2A2
    Isotype
    IgG
    Top Product
    Discover our top product AP2A2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
    Autre désignation
    alpha2 Adaptin (AP2A2 Produits)
    Synonymes
    anticorps MGC99219, anticorps ADTAB, anticorps CLAPA2, anticorps HIP-9, anticorps HIP9, anticorps HYPJ, anticorps 2410074K14Rik, anticorps AF006990, anticorps AW146353, anticorps Adtab, anticorps C78001, anticorps L25, anticorps adaptor related protein complex 2 alpha 2 subunit, anticorps adaptor related protein complex 2 alpha 2 subunit L homeolog, anticorps adaptor-related protein complex 2, alpha 2 subunit, anticorps AP2A2, anticorps ap2a2.L, anticorps Ap2a2
    Sujet

    Synonyms: AP-2 complex subunit alpha-2, 100 kDa coated vesicle protein C, Adaptor protein complex AP-2 subunit alpha-2, Adaptor-related protein complex 2 subunit alpha-2, Alpha-adaptin C, Alpha2-adaptin, Clathrin assembly protein complex 2 alpha-C large chain, Huntingtin yeast partner J, Huntingtin-interacting protein 9, HIP-9, Huntingtin-interacting protein J, Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit, AP2A2, ADTAB, CLAPA2, AP-2 complex subunit alpha-1, 100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Clathrin assembly protein complex 2 alpha-A large chain, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, AP2A1, ADTAA, CLAPA1

    Background: Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.

    ID gène
    161
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
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