TNFRSF6B anticorps (N-Term)

N° du produit ABIN499726

Détail du produit anti-TNFRSF6B anticorps

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF6B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: DcR3 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DcR3 precursor.

Purification: Ion exchange chromatography

Immunogène: Human DcR3 (N-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1/500 to 1/1000. An approximately 33 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL.

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TNFRSF6B

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Autre désignation: TNFRSF6B / DCR3 (TNFRSF6B Produits)

Synonymes: anticorps DCR3, anticorps DJ583P15.1.1, anticorps M68, anticorps M68E, anticorps TR6, anticorps dcr3, anticorps m68, anticorps tr6, anticorps TNF receptor superfamily member 6b, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps regulator of telomere elongation helicase 1, anticorps TNF receptor superfamily member 6b L homeolog, anticorps TNFRSF6B, anticorps tnfrsf11b, anticorps RTEL1, anticorps tnfrsf6b, anticorps tnfrsf6b.L

Sujet: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively, (1,2). Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis (1,2). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.Synonyms: Decoy receptor 3, Decoy receptor for Fas ligand

ID gène: 8771

UniProt: O95407