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GLE1 anticorps (Center)

GLE1 Reactivité: Humain, Rat, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499894
  • Antigène Voir toutes GLE1 Anticorps
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Épitope
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 16
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 14
    • 3
    Lapin
    Clonalité
    • 16
    • 1
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    Cet anticorp GLE1 est non-conjugé
    Application
    • 12
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to GLE1.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Gle1 antibody was raised against a 14 amino acid peptide near the center of human Gle1.
    Isotype
    IgG
    Top Product
    Discover our top product GLE1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Autre désignation
    GLE1 / GLE1L (GLE1 Produits)
    Synonymes
    anticorps Dmel\\CG14749, anticorps GLE1, anticorps GLE1L, anticorps LCCS, anticorps LCCS1, anticorps hGLE1, anticorps Gle1l, anticorps 4933405K21Rik, anticorps AA553313, anticorps CG14749 gene product from transcript CG14749-RA, anticorps nucleoporin GLE1, anticorps RNA export factor Gle1, anticorps GLE1, RNA export mediator, anticorps GLE1 RNA export mediator, anticorps GLE1 RNA export mediator (yeast), anticorps CG14749, anticorps CpipJ_CPIJ014147, anticorps SJAG_03847, anticorps GLE1, anticorps Gle1
    Sujet
    The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.Synonyms: GLE1-like protein, Nucleoporin GLE1
    ID gène
    2733
    NCBI Accession
    NP_001003722
    UniProt
    Q53GS7
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