SEC16B anticorps (C-Term)

N° du produit ABIN500212

Détail du produit anti-SEC16B anticorps

Antigène: SEC16B (SEC16 Homolog B (SEC16B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC16B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Humna, Mouse, Rat

Purification: Peptide affinity chromatography

Immunogène: LZTR2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LZTR2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SEC16B

Antigène: SEC16B (SEC16 Homolog B (SEC16B))

Autre désignation: SEC16B (SEC16B Produits)

Synonymes: anticorps LZTR2, anticorps PGPR-p117, anticorps RGPR, anticorps SEC16S, anticorps Lztr2, anticorps Rgpr, anticorps Rgpr-p117, anticorps RGPR-p117, anticorps SEC16 homolog B, endoplasmic reticulum export factor, anticorps SEC16 homolog B (S. cerevisiae), anticorps SEC16B, anticorps sec16b, anticorps Sec16b

Sujet: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.Synonyms: KIAA1928, LZTR2, Leucine zipper transcription regulator 2, Protein SEC16 homolog B, Protein transport protein Sec16B, RGPR, RGPR-p117, Regucalcin gene promoter region-related protein p117, SEC16B, SEC16S

ID gène: 89866

NCBI Accession: NP_149118

UniProt: Q96JE7