NDUFAF2 anticorps (C-Term)

N° du produit ABIN500282

Détail du produit anti-NDUFAF2 anticorps

Antigène: NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDUFAF2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: Mimitin antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur NDUFAF2

Antigène: NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))

Autre désignation: Mimitin (NDUFAF2 Produits)

Synonymes: anticorps B17.2L, anticorps MMTN, anticorps NDUFA12L, anticorps mimitin, anticorps Ndufa12l, anticorps RGD1560158, anticorps NDUFAF2, anticorps ndufa12l, anticorps zgc:101036, anticorps 1810058I14Rik, anticorps C86051, anticorps NADH:ubiquinone oxidoreductase complex assembly factor 2, anticorps NADH:ubiquinone oxidoreductase complex assembly factor 2 L homeolog, anticorps NADH dehydrogenase (ubiquinone) complex I, assembly factor 2, anticorps NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2, anticorps NDUFAF2, anticorps Ndufaf2, anticorps ndufaf2.L, anticorps ndufaf2

Sujet: Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80 % of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.Synonyms: B17.2-like, Myc-induced mitochondrial protein, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, NDUFA12L, NDUFAF2

ID gène: 91942

NCBI Accession: NP_777549

UniProt: Q8N183

Pathways: SARS-CoV-2 Protein Interactome