SLC9A1 anticorps (C-Term, N-Term)

N° du produit ABIN500339

Détail du produit anti-SLC9A1 anticorps

Antigène: SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))

Épitope: C-Term, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC9A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SLC9A1 / NHE1 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Nhe-1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human Nhe-1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur SLC9A1

Antigène: SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))

Autre désignation: SLC9A1 / NHE1 (SLC9A1 Produits)

Synonymes: anticorps AT-NHX1, anticorps ATNHX, anticorps ATNHX1, anticorps NA(+)/H(+) ANTIPORTER, anticorps Na+/H+ exchanger 1, anticorps T21B4.60, anticorps T21B4_60, anticorps AW554487, anticorps Apnh, anticorps Nhe1, anticorps swe, anticorps NHE-1, anticorps NHE1, anticorps APNH, anticorps Na+/H+ exchanger 1, anticorps solute carrier family 9 (sodium/hydrogen exchanger), member 1, anticorps solute carrier family 9 member A1, anticorps NHX1, anticorps Slc9a1, anticorps SLC9A1

Sujet: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.Synonyms: APNH, APNH1, Na(+)/H(+) antiporter, Na(+)/H(+) exchanger 1, Sodium/hydrogen exchanger 1, Solute carrier family 9 member 1, amiloride-sensitive

ID gène: 6548

UniProt: P19634

Pathways: Glycosaminoglycan Metabolic Process, Proton Transport