PLEKHM2
Reactivité: Humain
ELISA, WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Antigène
PLEKHM2
(Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
anticorps zgc:194971, anticorps RP11-169K16.1, anticorps SKIP, anticorps 2310034J19Rik, anticorps AI854247, anticorps mKIAA0842, anticorps pleckstrin homology and RUN domain containing M2, anticorps pleckstrin homology domain containing, family M (with RUN domain) member 2, anticorps PLEKHM2, anticorps plekhm2, anticorps Plekhm2
Sujet
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.Synonyms: KIAA0842, PH domain-containing family M member 2, Pleckstrin homology domain-containing family M member 2, SKIP, Salmonella-induced filaments A and kinesin-interacting protein, SifA and kinesin-interacting protein