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VGLL4 anticorps (AA 220-270) (Alexa Fluor 680)

VGLL4 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal Alexa Fluor 680
N° du produit ABIN5012391
  • Antigène Voir toutes VGLL4 Anticorps
    VGLL4 (Vestigial Like 4 (VGLL4))
    Épitope
    • 14
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 220-270
    Reactivité
    • 31
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 31
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VGLL4 est conjugé à/à la Alexa Fluor 680
    Application
    • 27
    • 12
    • 11
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human VGLL4
    Isotype
    IgG
    Top Product
    Discover our top product VGLL4 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    VGLL4 (Vestigial Like 4 (VGLL4))
    Autre désignation
    VGLL4 (VGLL4 Produits)
    Synonymes
    anticorps DKFZp459C0333, anticorps VGL-4, anticorps BC048841, anticorps vestigial-like family member 4, anticorps vestigial like family member 4, anticorps Vgll4, anticorps VGLL4
    Sujet

    Synonyms: Transcription cofactor vestigial like protein 4, Vestigial like protein 4, VGL 4, VGLL4, VGLL4_HUMAN.

    Background: The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-4 (vestigial-like protein 4) is a 290 amino acid nuclear protein that interacts with TEF-1 and MEF-2. Vgl-4 is the only member of the vestigial-like family that is expressed in heart. Overexpression of Vgl-4 in cardiac myocytes interferes with basal expression and ?-adrenergic receptor-dependent activation of a TEF-1 dependent skeletal ?actin promoter. This suggests that Vgl-4 counteracts ?-adrenergic activation of gene expression in cardiomyocytes. There are two isoforms of Vgl-4 that are produced as a result of alternative splicing events.

    ID gène
    9686
    UniProt
    Q14135
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