LGALS13 anticorps

N° du produit ABIN5026980

Détail du produit anti-LGALS13 anticorps

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS13 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Protein G Chromatography

Immunogène: A full length human Galectin-13 protein was used as the immunogen for this antibody.

Clone: ABM4E42

Isotype: IgG2b kappa

Information d'application

Indications d'application: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur LGALS13

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Autre désignation: Galectin 13 (LGALS13 Produits)

Synonymes: anticorps GAL13, anticorps PLAC8, anticorps PP13, anticorps Gal-11, anticorps Gal-13, anticorps Gal11, anticorps gal-13, anticorps galectin 13, anticorps avian beta-defensin 13, anticorps LGALS13, anticorps AvBD13

Sujet: Galectin-13 (Gal-13) is a glycan-binding protein that regulates innate and adaptive immune responses. It is predominantly expressed by the syncytiotrophoblast and released from the placenta into the maternal circulation. It has the ability to induce apoptosis of activated T cells in vitro, and divert and kill T cells as well as macrophages in the maternal decidua. Gal-13 with its anti-inflammatory functions plays a role in regulation of maternal immune system, a lack of gal-13 contribute to an imbalance in inflammation processes in the placenta during pregnancy and therefore influences development of gestational diabetes mellitus (GDM). Gal-13 levels are low in the first trimester of pregnancy that confers a higher risk for developing pre-eclampsia later in pregnancy.

Poids moléculaire: 32 kDa

ID gène: 29124

UniProt: Q9UHV8