ASAP1 anticorps (AA 912-1115)

N° du produit ABIN5027041

Détail du produit anti-ASAP1 anticorps

Antigène: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Épitope: AA 912-1115

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASAP1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant ASAP1 protein (amino acids 912-1115) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur ASAP1

Antigène: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Autre désignation: ASAP1 (ASAP1 Produits)

Synonymes: anticorps AV239055, anticorps DEF-1, anticorps Ddef1, anticorps PAP, anticorps mKIAA1249, anticorps s19, anticorps AMAP1, anticorps CENTB4, anticorps DDEF1, anticorps PAG2, anticorps ZG14P, anticorps ASAP1, anticorps ddef1, anticorps Asap1, anticorps si:ch211-160i2.3, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain1, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1, anticorps toxic extracellular endopeptidase, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a, anticorps Asap1, anticorps ASAP1, anticorps asaP1, anticorps asap1, anticorps asap1.L, anticorps asap1a

Sujet: ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and differentiation-enhancing factor 1 or DDEF1 is an ADP-ribosylation factor (ARF) GTPase-activating protein with two known isoforms: ASAP1a and ASAP1b (125 and 126 kDa, respectively). ASAP contains a pleckstrin homology (PH) domain, a zinc finger motif, 3 ankyrin repeats, a proline-rich region containing several SH3 ligand motifs, and an SH3 domain. GTPase-activating property of ASAP1 is induced by phosphatidylinositol 4,5-biphosphate (PIP2) of the PH domain. ASAP1 plays an important role in cytoskeleton remodeling and regulation of membrane trafficking. ASAP1 acts as a proto-oncogene in breast cancer and other malignant tumors. ASAP is highly expressed in brain tissue.

Poids moléculaire: 115 kDa

ID gène: 13196

UniProt: Q9QWY8