CRHR2 anticorps (AA 1-200)

N° du produit ABIN5027120

Détail du produit anti-CRHR2 anticorps

Antigène: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Épitope: AA 1-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRHR2 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant CRHR2 protein (amino acids 1-200) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5-2.0 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CRHR2

Antigène: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Autre désignation: CRHR2 (CRHR2 Produits)

Synonymes: anticorps CRF-RB, anticorps CRF2, anticorps CRFR2, anticorps HM-CRF, anticorps CRF-R2, anticorps CRFR2alpha, anticorps CRFR2beta, anticorps Crfr2, anticorps Crf2r, anticorps CRH-R2, anticorps crhr2-A, anticorps corticotropin releasing hormone receptor 2, anticorps corticotropin releasing hormone receptor 2 S homeolog, anticorps CRHR2, anticorps Crhr2, anticorps crhr2.S

Sujet: CRHR2 (CRF2R, CRH2R) (corticotropin releasing hormone receptor 2) belongs to the G-protein coupled receptor 2 family. This receptor has high affinity for corticotropin releasing hormone (CRH) and may also bind to CRH-related peptides, such as, urocortin. The human CRHR2 gene contains 12 exons. Three major functional isoforms have been reported: alpha, beta and gamma encoded by transcripts with alternative first exons which differ from each other by signal sequence and extra-cellular domain. CRH is synthesized in the hypothalamus and plays an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge. CRHR2 has high expression in brain, caudate nucleus, cerebrum, colon, endometrium, etc.

Poids moléculaire: 46 kDa

ID gène: 1395

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour