NR2F6 anticorps (AA 210-400)

N° du produit ABIN5027402

Détail du produit anti-NR2F6 anticorps

Antigène: NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))

Épitope: AA 210-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2F6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant NR2F6 protein (amino acids 210-400) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur NR2F6

Antigène: NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))

Autre désignation: NR2F6 (NR2F6 Produits)

Synonymes: anticorps EAR-2, anticorps EAR2, anticorps ERBAL2, anticorps AV090102, anticorps COUP-TF3, anticorps Erbal2, anticorps COUP(II), anticorps NR2F6, anticorps couptf2, anticorps fc94g11, anticorps wu:fc94g11, anticorps zgc:77259, anticorps ear-2, anticorps ear2, anticorps erbal2, anticorps nr2f6l, anticorps wu:fc72d04, anticorps zgc:77260, anticorps nuclear receptor subfamily 2 group F member 6, anticorps nuclear receptor subfamily 2, group F, member 6, anticorps nuclear receptor subfamily 2, group F, member 6a, anticorps nuclear receptor subfamily 2 group F member 6 L homeolog, anticorps nuclear receptor subfamily 2, group F, member 6b, anticorps NR2F6, anticorps Nr2f6, anticorps nr2f6a, anticorps nr2f6.L, anticorps nr2f6, anticorps nr2f6b

Sujet: NR2F6 (Nuclear receptor subfamily 2 group F member 6) is a nuclear zinc-finger orphan receptor which acts as a critical PKC (protein kinase C) substrate and essential regulator of CD4(+) T cell activation responses. It Inhibits NFATC (Nuclear factor of activated T-cells) transcription factor DNA binding and subsequently its transcriptional activity. It acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. It is involved in development of forebrain circadian clock.

Poids moléculaire: 45 kDa

ID gène: 2063

UniProt: P10588

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism