PACS1 anticorps (AA 150-400)

N° du produit ABIN5027422

Détail du produit anti-PACS1 anticorps

Antigène: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Épitope: AA 150-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACS1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant PACS-1 protein (amino acids 150-400) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-3 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur PACS1

Antigène: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Autre désignation: PACS-1 (PACS1 Produits)

Synonymes: anticorps MRD17, anticorps AI325977, anticorps Pacs-1, anticorps phosphofurin acidic cluster sorting protein 1, anticorps PACS1, anticorps Pacs1

Sujet: PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.

Poids moléculaire: 106 kDa

ID gène: 55690

UniProt: Q6VY07