SPIB anticorps (AA 50-260)

N° du produit ABIN5027543

Détail du produit anti-SPIB anticorps

Antigène: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Épitope: AA 50-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPIB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant Spi-B protein (amino acids 50-260) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur SPIB

Antigène: SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Autre désignation: Spi-B (SPIB Produits)

Synonymes: anticorps spi-b, anticorps spib, anticorps spiba, anticorps SPI-B, anticorps B42b-like, anticorps Spi-B, anticorps Spi-B transcription factor L homeolog, anticorps Spi-B transcription factor, anticorps Spi-B transcription factor (Spi-1/PU.1 related), anticorps spib.L, anticorps SPIB, anticorps Spib

Sujet: Spi-B belongs to the ETS family transcription containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N- terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.

Poids moléculaire: 28 kDa

ID gène: 6689

UniProt: Q01892