MAP1LC3A anticorps (AA 1-12) (Alkaline Phosphatase (AP))
-
- Antigène Voir toutes MAP1LC3A Anticorps
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
-
Épitope
- AA 1-12
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MAP1LC3A est conjugé à/à la Alkaline Phosphatase (AP)
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,Detects ~14 kDa. Band at 50 kDa is LC3A complex.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Peptide Affinity Purified
- Immunogène
- Synthetic peptide from the N-terminal of Human LC3A (aa. 1-12)
- Isotype
- IgG
- Top Product
- Discover our top product MAP1LC3A Anticorps primaire
-
-
- Indications d'application
-
- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Commentaires
-
A 1:1000 dilution of ABIN5065912 was sufficient for detection of LC3A in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
-
- Antigène
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- Autre désignation
- LC3A (MAP1LC3A Produits)
- Synonymes
- anticorps ATG8E, anticorps LC3, anticorps LC3A, anticorps MAP1ALC3, anticorps MAP1BLC3, anticorps 1010001H21Rik, anticorps 4922501H04Rik, anticorps LC3a, anticorps MGC69006, anticorps zgc:77094, anticorps MGC89867, anticorps MAP1LC3A, anticorps map1lc3a, anticorps microtubule associated protein 1 light chain 3 alpha, anticorps microtubule-associated protein 1 light chain 3 alpha, anticorps microtubule associated protein 1 light chain 3 alpha S homeolog, anticorps MAP1LC3A, anticorps Map1lc3a, anticorps map1lc3a.S, anticorps map1lc3a
- Sujet
- Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17 kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy, once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3A is one of three isoforms which exhibits abundant expression in the heart, brain, liver, skeletal muscle, and testis but is absent in thymus and peripheral blood leukocytes.
- ID gène
- 84557
- NCBI Accession
- NP_115903
- UniProt
- Q9H492
- Pathways
- Autophagy
-